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Program - SSSD2019

Wednesday April 10th

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Registration (open from 10:00)

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11.00 - 11.15 Opening with Welcome Remarks from the chair of the local organising committee

Malin Flodström-Tullberg

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11.15 - 12.45 Session 1: Islet physiology and pathophysiology

Chair: Per-Ola Carlsson

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Islet cell exocytosis in type 2 diabetes

Sebastian Barg, Uppsala University, Sweden

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Diabetes from a cellular perspective

Lena Eliasson, Lund University, Sweden

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Oral abstract presentations

Gonzalo Sanchez GABAergic signaling in the primary cilium of pancreatic islet β-

cells

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12.45 - 14.15 Lunch & Exhibition

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13.30 - 14.00 Lunch seminar on scientific publications

Mikael Rydén, Karolinska Institutet, co-editor of Diabetologia

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14.15 - 15.30 Session 1: Islet physiology and pathophysiology (continued)

Chair: Valdemar Grill

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Oral abstract presentations

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Anders Tengholm Glucose-induced changes of α-cell cAMP control glucagon release during hypoglycaemia

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Luis Rodrigo Cataldo PP1R1A, a novel regulator of the GLP1R-amplifying glucose stimulated insulin secretion in β-cells

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Ruifeng Shi The expression and function of Clec11a in human islets

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Hanna Liljebäck Fewer islets survive from first transplantation than second transplantation: evaluation of intraportal islet transplantation in mice

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Anja Brboric Developing techniques for expansion and culture of neural crest stem cells isolated from human bone marrow to improve the survival and function of transplanted islets of Langerhans

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Sara Ullsten Increased susceptibility for immune attack of highly blood perfused, highly metabolically active pancreatic islets

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15.30 - 16.00 Coffee break and exhibition

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16.00 - 17.00 Oral abstract presentations (continued)

Chair: Mikael Rydén

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Type 1 diabetes – clinical aspects

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Anna Korsgaard Berg The economic additional expenditure related to skin problems in patients using insulin pump and/or glucose sensor in a Danish context

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Maarit K Koskinen Longitudinal pattern of first phase insulin response is associated with genetic factors outside class II HLA region in children with multiple autoantibodies

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Anmol Kumar The association between FGF23 and bone mineral density in type 1 diabetes with different stages of renal disease

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Fanny J Jansson High remnant cholesterol predicts progression of diabetic nephropathy in type 1 diabetes

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Marika Eriksson Association between blood pressure measured ambulatory and cerebral small-vessel disease in type 1 diabetes

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17.00 - 18.15 Knud Lundbeck Award lecture:

Chair: Björn Olav Åsvold

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New insights into genetics of metabolic health and disease – lessons to be used in precision medicine

Torben Hansen, University of Copenhagen, Denmark

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18.30 Welcome reception, exhibition

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Thursday April 11th

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08:30 - 09.45 Session 2: Imaging in diabetes

Chair: Joey Lau-Börjesson

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Eyelets in diabetes research and clinic

Per-Olof Berggren, Karolinska Institutet, Sweden

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Metabolic imaging of adipose tissue in diabetes

Kirsi Virtanen, University of Eastern Finland, Finland

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09.45 - 10.45 Oral abstract presentations

Chair: Lena Eliasson

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Infections and islet disease

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Magdalena A Mazur Type III interferons (IFNλs) are expressed in the human type 1 diabetes pancreas at disease onset, upregulate HLA class I expression and protect beta cells from Coxsackievirus infection

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Carmen Herrera Hidalgo Neonatal infections alter islet maturation and long-term glucose homeostasis

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Kristel Parv Phagocytosis and efferocytosis by pancreatic macrophages

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Virginia M Stone A hexavalent vaccine covering all Coxsackievirus B (CVB) serotypes protects against acute CVB infection and CVB-induced diabetes in mice

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Isabel Diaz Lozano Identifying novel biomarkers for virus-induced diabetes using an experimental animal model

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10.45 - 11.15 Coffee break and exhibition

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11.15 - 12.00 The Swedish Child Diabetes Foundation's Johnny Ludvigsson Nordic Prize lecture:

Chair: Johnny Ludvigsson

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Quality of care – the answer is blowing in the registries

Jannet Svensson, Copenhagen University Hospital, Denmark

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12.00 - 12.45 The Swedish Child Diabetes Foundation's Johnny Ludvigsson

Prize to a Young Swedish Scientist lecture:

Chair: Johnny Ludvigsson

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Beta-cell replacement in type 1 diabetes

Joey Lau Börjesson, Uppsala University, Sweden

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12.45 - 14.00 Lunch and exhibition

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13.30 - 14.00 Lunch seminar on academic innovations

Patrik Blomquist, KI Innovation, Stockholm, Sweden

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14.00 - 15.15 Session 3: Pathophysiology and prevention of type 1 diabetes

Chair: Malin Flodström-Tullberg

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Beta cell stress and development of Type 1 diabetes

Johnny Ludvigsson, Linköping University, Sweden

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Viruses and type 1 diabetes - prospects for prevention

Heikki Hyöty, University of Tampere, Finland

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15.15 - 15.45 Coffee break and exhibition

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15.45 – 17.00 Oral presentations (two parallel sessions)

 

Hall 1 - Type 2 diabetes and LADA – clinical aspects

Chair: Daniel Andersson

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Maria Houborg Petersen High intensity interval training combining biking and rowing markedly improves insulin sensitivity, body composition and VO2max

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Maria Hornstrup Christensen Future health and gestational diabetes - the FUDGE study

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Anna P Westberg The impact of maternal weight in pregnancy on glucose tolerance and insulin resistance in non-diabetic offspring

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Sofia Carlsson Type 2 diabetes and occupation; professional drivers, manufacturing workers and cleaners are at high risk; evidence from all Swedish employees 2006-2015

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Nikolaos Tertipis High-throughput metabolomics for early detection of individuals at increased risk for type 2 diabetes

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Ingrid K Hals Insulin treatment vs. sitagliptin does not affect deterioration of insulin secretion in LADA patients. Results from a 21 month randomized study

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Rebecka Hjort Physical activity and genetic susceptibility in relation to the risk of latent autoimmune diabetes in adults and type 2 diabetes

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Hall 2 - Immunological aspects of type 1 diabetes

Chair: Johanna Lempainen

 

Louise Magnusson Identification of altered immune cell subsets in patients with autoimmune endocrine diseases by mass cytometry

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Zhengkang Luo Kinetics of immune cell responses in the multiple low dose streptozotocin mouse model of type 1 diabetes

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Fabricia Dietrich Immunological effects of GAD-alum injection into the lymph node in recent onset type 1 diabetes

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Hugo Barcenilla Mass cytometry identifies regulatory T and Natural Killer cell subsets that are increased in individuals at high risk for type 1 diabetes

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Camilla Skoglund Increased levels of neutrophil extracellular trap (NET) remnants as well as mitochondrial and nuclear DNA in newly diagnosed type 1 diabetes children

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Kailash Singh Role of regulatory B cells in clinical and experimental type 1 diabetes

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17.15 - 18.30 Session 4: Clinical Science and Care

Chair: Per-Ola Carlsson

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Glucose sensor technologies in the management of type 1 diabetes

Jan Bolinder, Karolinska Institutet, Sweden

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Insulin pumps, from simple injection aid to advanced technology

Anders Frid, Lund University, Sweden

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18.30 – 19.15 General assembly of SSSD. Presentation of next year´s meeting

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19.30 Congress Dinner World Trade Center

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Friday April 12th

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08:30 – 09:00 Session 4: Clinical Science and Care, continued

Chair: Per-Ola Carlsson

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News from the Swedish National Diabetes Register (NDR)

Soffia Gudbjörnsdottir University of Gothenburg, Sweden

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09.00 - 09.30 SSSD Young Investigator Awards

Chair: Björn-Olav Åsvold

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Insulin secretion depends on intra-islet glucagon signaling

Berit Svendsen, University of Copenhagen, Denmark

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Sodium glucose transporter 2 inhibitors and risk of serious adverse events: nationwide register based cohort study

Peter Ueda, Karolinska Institutet, Sweden

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09.30 - 10.45 Session 5: Metabolism and inflammation in type 2 diabetes

Chair: Anna Krook

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Novo Nordisk Foundation Award Lecture:

Incretin therapy - Lessons learned and future directions

Bo Ahren, Lund University, Sweden

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Human adipose tissue and metabolic health

Kirsty Spalding, Karolinska Institutet, Sweden

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10.45 - 11.15 Coffee break (sponsored by AstraZeneca)

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11.15 - 12.30 Session 6: Precision Medicine and Drug Discovery

Chair: Olov Andersson

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Translational studies to enable tailored treatment of type 2 diabetes

Anders Rosengren. University of Gothenburg, Sweden

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Towards the development of microfluidic multi-tissue models for diabetes research and drug discovery

Volker Lauschke, Karolinska Institutet, Sweden

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12.30 - 12.45 Closing of the meeting

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12.45 Lunch and farewell

Female Scientist Using Microscope

The Scandinavian Society for the Study of Diabetes

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