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Program - SSSD2019

Wednesday April 10th

Registration (open from 10:00)

11.00 - 11.15 Opening with Welcome Remarks from the chair of the local organising committee

Malin Flodström-Tullberg

11.15 - 12.45 Session 1: Islet physiology and pathophysiology

Chair: Per-Ola Carlsson

Islet cell exocytosis in type 2 diabetes

Sebastian Barg, Uppsala University, Sweden

Diabetes from a cellular perspective

Lena Eliasson, Lund University, Sweden

Oral abstract presentations

Gonzalo Sanchez GABAergic signaling in the primary cilium of pancreatic islet β-


12.45 - 14.15 Lunch & Exhibition

13.30 - 14.00 Lunch seminar on scientific publications

Mikael Rydén, Karolinska Institutet, co-editor of Diabetologia

14.15 - 15.30 Session 1: Islet physiology and pathophysiology (continued)

Chair: Valdemar Grill

Oral abstract presentations

Anders Tengholm Glucose-induced changes of α-cell cAMP control glucagon release during hypoglycaemia

Luis Rodrigo Cataldo PP1R1A, a novel regulator of the GLP1R-amplifying glucose stimulated insulin secretion in β-cells

Ruifeng Shi The expression and function of Clec11a in human islets

Hanna Liljebäck Fewer islets survive from first transplantation than second transplantation: evaluation of intraportal islet transplantation in mice

Anja Brboric Developing techniques for expansion and culture of neural crest stem cells isolated from human bone marrow to improve the survival and function of transplanted islets of Langerhans

Sara Ullsten Increased susceptibility for immune attack of highly blood perfused, highly metabolically active pancreatic islets

15.30 - 16.00 Coffee break and exhibition

16.00 - 17.00 Oral abstract presentations (continued)

Chair: Mikael Rydén

Type 1 diabetes – clinical aspects

Anna Korsgaard Berg The economic additional expenditure related to skin problems in patients using insulin pump and/or glucose sensor in a Danish context

Maarit K Koskinen Longitudinal pattern of first phase insulin response is associated with genetic factors outside class II HLA region in children with multiple autoantibodies

Anmol Kumar The association between FGF23 and bone mineral density in type 1 diabetes with different stages of renal disease

Fanny J Jansson High remnant cholesterol predicts progression of diabetic nephropathy in type 1 diabetes

Marika Eriksson Association between blood pressure measured ambulatory and cerebral small-vessel disease in type 1 diabetes

17.00 - 18.15 Knud Lundbeck Award lecture:

Chair: Björn Olav Åsvold

New insights into genetics of metabolic health and disease – lessons to be used in precision medicine

Torben Hansen, University of Copenhagen, Denmark

18.30 Welcome reception, exhibition

Thursday April 11th

08:30 - 09.45 Session 2: Imaging in diabetes

Chair: Joey Lau-Börjesson

Eyelets in diabetes research and clinic

Per-Olof Berggren, Karolinska Institutet, Sweden

Metabolic imaging of adipose tissue in diabetes

Kirsi Virtanen, University of Eastern Finland, Finland

09.45 - 10.45 Oral abstract presentations

Chair: Lena Eliasson

Infections and islet disease

Magdalena A Mazur Type III interferons (IFNλs) are expressed in the human type 1 diabetes pancreas at disease onset, upregulate HLA class I expression and protect beta cells from Coxsackievirus infection

Carmen Herrera Hidalgo Neonatal infections alter islet maturation and long-term glucose homeostasis

Kristel Parv Phagocytosis and efferocytosis by pancreatic macrophages

Virginia M Stone A hexavalent vaccine covering all Coxsackievirus B (CVB) serotypes protects against acute CVB infection and CVB-induced diabetes in mice

Isabel Diaz Lozano Identifying novel biomarkers for virus-induced diabetes using an experimental animal model

10.45 - 11.15 Coffee break and exhibition

11.15 - 12.00 The Swedish Child Diabetes Foundation's Johnny Ludvigsson Nordic Prize lecture:

Chair: Johnny Ludvigsson

Quality of care – the answer is blowing in the registries

Jannet Svensson, Copenhagen University Hospital, Denmark

12.00 - 12.45 The Swedish Child Diabetes Foundation's Johnny Ludvigsson

Prize to a Young Swedish Scientist lecture:

Chair: Johnny Ludvigsson

Beta-cell replacement in type 1 diabetes

Joey Lau Börjesson, Uppsala University, Sweden

12.45 - 14.00 Lunch and exhibition

13.30 - 14.00 Lunch seminar on academic innovations

Patrik Blomquist, KI Innovation, Stockholm, Sweden

14.00 - 15.15 Session 3: Pathophysiology and prevention of type 1 diabetes

Chair: Malin Flodström-Tullberg

Beta cell stress and development of Type 1 diabetes

Johnny Ludvigsson, Linköping University, Sweden

Viruses and type 1 diabetes - prospects for prevention

Heikki Hyöty, University of Tampere, Finland

15.15 - 15.45 Coffee break and exhibition

15.45 – 17.00 Oral presentations (two parallel sessions)


Hall 1 - Type 2 diabetes and LADA – clinical aspects

Chair: Daniel Andersson

Maria Houborg Petersen High intensity interval training combining biking and rowing markedly improves insulin sensitivity, body composition and VO2max

Maria Hornstrup Christensen Future health and gestational diabetes - the FUDGE study

Anna P Westberg The impact of maternal weight in pregnancy on glucose tolerance and insulin resistance in non-diabetic offspring

Sofia Carlsson Type 2 diabetes and occupation; professional drivers, manufacturing workers and cleaners are at high risk; evidence from all Swedish employees 2006-2015

Nikolaos Tertipis High-throughput metabolomics for early detection of individuals at increased risk for type 2 diabetes

Ingrid K Hals Insulin treatment vs. sitagliptin does not affect deterioration of insulin secretion in LADA patients. Results from a 21 month randomized study

Rebecka Hjort Physical activity and genetic susceptibility in relation to the risk of latent autoimmune diabetes in adults and type 2 diabetes

Hall 2 - Immunological aspects of type 1 diabetes

Chair: Johanna Lempainen


Louise Magnusson Identification of altered immune cell subsets in patients with autoimmune endocrine diseases by mass cytometry

Zhengkang Luo Kinetics of immune cell responses in the multiple low dose streptozotocin mouse model of type 1 diabetes

Fabricia Dietrich Immunological effects of GAD-alum injection into the lymph node in recent onset type 1 diabetes

Hugo Barcenilla Mass cytometry identifies regulatory T and Natural Killer cell subsets that are increased in individuals at high risk for type 1 diabetes

Camilla Skoglund Increased levels of neutrophil extracellular trap (NET) remnants as well as mitochondrial and nuclear DNA in newly diagnosed type 1 diabetes children

Kailash Singh Role of regulatory B cells in clinical and experimental type 1 diabetes

17.15 - 18.30 Session 4: Clinical Science and Care

Chair: Per-Ola Carlsson

Glucose sensor technologies in the management of type 1 diabetes

Jan Bolinder, Karolinska Institutet, Sweden

Insulin pumps, from simple injection aid to advanced technology

Anders Frid, Lund University, Sweden

18.30 – 19.15 General assembly of SSSD. Presentation of next year´s meeting

19.30 Congress Dinner World Trade Center

Friday April 12th

08:30 – 09:00 Session 4: Clinical Science and Care, continued

Chair: Per-Ola Carlsson

News from the Swedish National Diabetes Register (NDR)

Soffia Gudbjörnsdottir University of Gothenburg, Sweden

09.00 - 09.30 SSSD Young Investigator Awards

Chair: Björn-Olav Åsvold

Insulin secretion depends on intra-islet glucagon signaling

Berit Svendsen, University of Copenhagen, Denmark

Sodium glucose transporter 2 inhibitors and risk of serious adverse events: nationwide register based cohort study

Peter Ueda, Karolinska Institutet, Sweden

09.30 - 10.45 Session 5: Metabolism and inflammation in type 2 diabetes

Chair: Anna Krook

Novo Nordisk Foundation Award Lecture:

Incretin therapy - Lessons learned and future directions

Bo Ahren, Lund University, Sweden

Human adipose tissue and metabolic health

Kirsty Spalding, Karolinska Institutet, Sweden

10.45 - 11.15 Coffee break (sponsored by AstraZeneca)

11.15 - 12.30 Session 6: Precision Medicine and Drug Discovery

Chair: Olov Andersson

Translational studies to enable tailored treatment of type 2 diabetes

Anders Rosengren. University of Gothenburg, Sweden

Towards the development of microfluidic multi-tissue models for diabetes research and drug discovery

Volker Lauschke, Karolinska Institutet, Sweden

12.30 - 12.45 Closing of the meeting

12.45 Lunch and farewell

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